We have seen many research groups trying to explore the usefulness of green tea for reduction in heart disease (bad cholesterol), increase in metabolic rate (fat oxidization) prevention of Alzheimer’s or Parkinson’s diseases, lowering incidence of cancers and weight reduction.
Now researchers from Meharry Medical College in Nashville, Tenn lead Dr. Ayman Al-Hendy , have found that green tea extract shows promise as a treatment for uterine fibroids. The key ingredient responsible for this activity is "epigallocatechin gallate (EGCG)". The researchers investigated the effect of epigallocatechin gallate on rat leiomyoma (ELT3) cells in vitro and in a nude mice model. ELT3 cells were treated with various concentrations of EGCG. Cell proliferation, proliferation cell nuclear antigen (PCNA), and cyclin-dependent kinase 4 (Cdk4) protein levels were evaluated. As per the claim by the researchers, EGCG significantly decreased PCNA and Cdk4 protein levels. The authotrs conclude that EGCG effectively inhibits proliferation and induces apoptosis in rat ELT3 uterine leiomyoma cells in vitro and in vivo.
Ref : http://www.ajog.org/article/S0002-9378%2809%2902102-4/fulltext
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