Study shows how a drug-lead compound suppresses tumour formation: A team of scientists from the National University of Singapore's (NUS) Department of Biological Sciences and Mechanobiology Institute have discovered how a drug-led compound - a compound that is undergoing preclinical trials as a potential drug - can deprive cancer cells of energy and stop them from growing into a tumour. This drug-led compound is named BPTES (see below structure). This is the the first detailed descriptions of precisely how BPTES inhibits glutaminase....
Ref : http://www.pnas.org/content/109/20/7705.full
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