FDA Approves Otezla (apremilast) for Moderate to Severe Plaque Psoriasis

 In continuation of my update on Apremilast (brand name Otezla) is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous production of TNF-alpha from human rheumatoid synovial cells. It has anti-inflammatory activity.

FDA Approves Otezla (apremilast) for Moderate to Severe Plaque Psoriasis