Showing posts with label Fycompa (perampanel). Show all posts
Showing posts with label Fycompa (perampanel). Show all posts

Sunday, October 28, 2012

FDA Clears Eisai’s Epilepsy Drug Fycompa


We know that, Fycompa (see structure, perampanel) is a selective, non-competitive AMPA receptor antagonist discovered by the research teams at Eisai laboratories. The development of an AMPA antagonist compound with a favourable pharmacokinetic and safety profile arose after the AMPA receptor was identified as a promising target for drug development. The AMPA receptor is widely present in almost all excitatory neurons. It is believed to play a role in a large number of central nervous system diseases with similar neuropathology.