Researchers from Johns Hopkins University, BaltimoreLostartan, lead by have found that, Dr.Enid R. Neptune Losartan a drug used widely in the clinic (e.g., to treat high blood pressure),
reduced lung disease in mice caused by exposure to cigarette smoke.
Losartan blocks the protein angiotensin receptor type 1, and its effects
on cigarette smoke-induced lung injury were a result of the fact that
blocking angiotensin receptor type 1 leads to a decrease in levels of
the soluble molecule TGF-beta. The authors therefore suggest that other
TGF-beta-targeted therapeutics might also be viable candidates for the
treatment of chronic obstructive pulmonary disease, COPD....
Ref : http://www.jci.org/articles/view/46215?search[article_text]=&search[authors_text]=Enid+Neptune
