Med-Chemist : "Quintessential Medicinal Chemistry"
Thursday, April 30, 2009
After Avian Flu its now Swine Flu ...!.
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I am wondering how many flus ?. Human flu, Dog flu, Horse flu, Avian flu and Swine flu. In all these cases, the strains have "mutate...
Sunday, April 26, 2009
FDA's approval of phase II clinical trials of Bryostatin ( Alzheimer's disease)...
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Bryostatins are a group of macrolide lactones first discovered in the late 1960s in a species of bryozoan , Bugula neritina . It is be...
Sorafenib and vitamin K combo as anticancer drug against pancreas cancer....
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We know that Sorafenib , is a drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma) and advanced...
Friday, April 24, 2009
Melatonin as a potential anti-fibrotic drug ?
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Melatonin, N-(2-(5-methoxy-1H- indol-3-yl)ethyl)acetamide ) is a hormone found in all living creatures. It is naturally syn...
Wednesday, April 22, 2009
Synthesis of Serratezomine A (an alkaloid)...
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As synthetic chemists we are aware that, how difficult is to syntheize the natural products with lots of stereochemistry involved. Congrats ...
Tuesday, April 21, 2009
White light-activated antibacterial coating-a new weapon against superbugs ?
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I read in an article that infection costs the NHS around £1 billion per year and it is estimated that as many as 5,000 patients die each yea...
Vaccine for Enterotoxigenic E. coli?
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We know that Escherichia coli is a bacterium that normally lives in the intestines of humans and other animals. Most types of E. coli are h...
Sunday, April 19, 2009
Oral Etoricoxib as post surgery drug?
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Developed as an alternative to conventional non-steroidal anti-inflammatory drugs (NSAIDs), which can cause intestinal blee...
Simponi the first biologic therapy to be approved for rheumatologic diseases !
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We did know about the three 3 TNF inhinitors (namely-Infliximab , Etanercept and Adalimumab ) , the last still to be approved by U...
A New approach for the TB drug discovery ?
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We are aware that the development of new drugs to combat tuberculosis (TB) has become urgent, as strains of TB resistant to all major anti-T...
Wednesday, April 15, 2009
Fluorescent anesthetic compound – a new avenues for drug discovery?
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We did know about the fluorescent biomarkers in drug discovery, especially to establish the mode of action of drugs. But this is somet...
Monday, April 13, 2009
Broccoli sprouts may help prevent stomach cancer !
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Pict., of Broccoli (Structures of DIM & Sulforaphane respectively) We knew that Broccoli has anticancer activity due to the...
Sunday, April 12, 2009
Niacin as one of the best and cheapest ways to manage cholesterol !
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Niacin (nicotinic acid or vitamin B3), has long been regarded as one of the most effective weapons in managing cholesterol. It can lower le...
Visualization of single ribonucleic acid in living cell achieved?
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Yes says a research group lead by Philip Santangelo , an Asst., Professor in the Wallace H. Coulter Department of Biomedical Engi...
Tuesday, April 7, 2009
New hope for patients suffering from Parkinson’s Disease ?
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A novel method for the treatment of patients suffering from parkinson's disease (and probably will be the first of its kind in...
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